data-id="" >PubMedhttps://pubmed.ncbi.nlm.nih.gov/28044278Understand spiciness: mechanism of TRPV1 channel activation …网页Epub 2017 Jan 2. Authors Fan Yang 1 , Jie Zheng 2 Affiliations 1 Department of Physiology and Membrane ... where it takes a "tail-up, head-down" configuration. Binding is mediated by both hydrogen bonds and van der Waals interactions. Upon binding, capsaicin stabilizes the open state of TRPV1 by "pull-and-contact" with the S4-S5 linker. ...
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